Overview
The Sarah W. Stedman Nutrition and Metabolism Center is an interdepartmental and interdisciplinary center for metabolic and nutritional research with strong ties to basic and clinical research groups on the Duke campus and beyond. Under the direction of Christopher B. Newgard, PhD, the center is building a unique program in metabolic and nutritional research that consists of three major areas of competency:
- Basic Science
We have recruited a cadre of world-class basic scientists who deploy interdisciplinary approaches to understand fundamental nutritional and metabolic regulatory mechanisms.
- Clinical Research
Led by Laura P. Svetkey, MD, our efforts are focused on translating basic science and epidemiological findings into well-designed clinical trials, ultimately leading to the development of new therapies for chronic diseases with a metabolic basis such as obesity, diabetes, heart disease, and cancer.
- Comprehensive Metabolic/Biomarker Profiling
We have developed a technology platform that includes mass spectrometry and nuclear magnetic resonance-based approaches for comprehensive metabolic analysis; multiplex assay systems for hormones of energy balance and cytokines; and physiologic measurements such as resting metabolic rate and body composition. The long-term goal is to generate personalized metabolic profiles that diagnose and direct the treatment of individuals with chronic diseases.