Jennifer B. Moss, PhD

 

Jennifer Moss, PhD came to Duke and the Stedman Center in 2005 as an assistant professor of Medicine, Division of Endocrinology, Metabolism, and Nutrition. Her scientific training includes studying insulin promoter activity at UCSF and heart development in the mouse at Harvard University. Prior to coming to Duke, she was an assistant research professor at Tufts University School of Medicine, where she helped initiate work on zebrafish pancreas development and the regeneration of adult zebrafish β cells. Through the use of the zebrafish as a whole animal system, the Moss lab has found that islet tissue can be regenerated after chemical or surgical ablation without the need for insulin therapy. The lab is currently developing a high throughput screen to evaluate potential drugs that will be applicable to biomedical therapies in diabetes and cancer. Another area of research in the lab is β cell neogenesis and the importance of the sonic hedgehog signaling pathway in this process.

 

Moss JB, Koustubhan P, Walter I, Moss LG. Regeneration of the Pancreas in Adult Zebrafish. 2005 (In Preparation).

diLorio PJ, Moss JB, Sbrogna JL, Karlstrom Ro, Moss LG. Sonic hedgehog is required early in pancreatic islet development. Dev Biol. 2002;244;75-84.

 

Moss JB, Xavier-Neto J, Shapiro MD, Nayeem SM, McCaffrey P, Drager UL, Rosenthal N. Dynamic patterns of retinoic acid synthesis and response in the developing mammalian heart. Dev Biol. 1998;199(1):55-77.