Faculty & Staff

Lillian F. Lien, MD

Medical Director, Duke Inpatient Diabetes Management

Assistant Professor of Medicine, Department of Medicine

Division of Endocrinology, Metabolism, and Nutrition

Sarah W. Stedman Nutrition and Metabolism Center

Duke University Medical Center

Lillian Lien, MD is Medical Director for Duke Hospital Inpatient Diabetes Management, Assistant Professor of Medicine, Division of Endocrinology, Metabolism and Nutrition, and a faculty member of Duke University’s Sarah W. Stedman Nutrition and Metabolism Center. Dr. Lien also completed Internal Medicine Residency and Endocrinology Fellowship training at Duke University Medical Center. She has long had an interest in quantitative research, beginning with her undergraduate work at Harvard University in Biomedical Engineering. Throughout her career, she has devoted her efforts to clinical research. In 2001, she received the Barton Haynes Research Support Award for her innovative work in optimizing the safe administration of intravenous insulin. Her research interests lie in the field of obesity and metabolism with a focus on metabolic syndrome, adipocytokines, and insulin resistance. She also received the 2006 Haynes Early Career Research Grant for junior faculty in the Duke Department of Medicine and was nominated for the 2008 Eugene Stead Dept. of Medicine Faculty Teaching Award.

She is a key investigator on local and national obesity - metabolic studies including: the STEDMAN Project (Study of the Effect of Diet on Metabolism And Nutrition), the Weight Loss Maintenance Clinical Trial, and the MURDOCK Horizon1 obesity project, which aims toward an innovative understanding of the biology of obesity and weight loss. In 2008, she also became Medical Director of Duke Inpatient Diabetes. Due to her above interests and experience, she has published in both the fields of obesity and inpatient diabetes management.

Publications:

Lien LF, Brown AJ, Ard JD, Loria C, Erlinger TP, Feldstein AC, Lin PH, Champagne CM, King AC, McGuire HL, Stevens VJ, Brantley PJ, Harsha DW, McBurnie MA, Appel LJ, Svetkey LP. “Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome.” Hypertension. Vol. 50, No. 4:p. 609-16, Oct 2007

Lien L, Spratt S, Woods Z, Osborne K, Feinglos M. “Optimizing Hospital Use of Intravenous Insulin: Improved hyperglycemic management and error reduction with a new nomogram” Endocrine Practice. Vol. 11, No. 4: p.240-253, July/Aug 2005

Lien L, Feinglos M. “Protease Inhibitor-Induced Diabetic Complications: Incidence, Management, and Prevention” Drug Safety. Vol. 28, No. 3: p.209-226, 2005

Lien L, Feinglos M. “Management of Obesity-Associated Type 2 Diabetes.” Chapter 12 in Nutrition and Diabetes:Pathophysiology and Management, ed. Opara E., CRC press: Boca Raton, FL, p.205-225, 2005

*Haqq AM, *Lien LF, Boan J, Arlotto M, Slentz CA, Muehlbauer MJ, Rochon J, Gallup, D, McMahon RL, Bain JR, Stevens R, Millington D, Butler MD, Newgard CB, Svetkey LP. “The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) Weight Loss Project: Rationale and Design.” Contemporary Clinical Trials. Vol. 26, No. 6: p.616-25, Dec 2005 *These authors contributed equally to the cited works.

Lien L, Whitson H, Grant, A, McNeill D. Multiple Endocrine Neoplasia Type 1 Presenting with Chronic and Persistent Diarrhea. Endocrine Practice. 2004;10:83-83.

Lien L, Bethel MA, Feinglos M. In-hospital Management of Type 2 Diabetes Mellitus. Medical Clinics of North America. 2004;88(No. 4):1085-1105.

Lien LF, Lane JD. “Pharmacologic factors affecting glycemic control.” Chapter in Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management, eds. Feinglos MN and Bethel MA, in press, 2008.

Davis ED, Harwood K, Midgett L, Mabrey M, Lien LF. “Implementation of a new intravenous insulin method on intermediate-care units in hospitalized patients.” Diabetes Educator. Vol. 31, No. 6: p.818-21, 823, Nov-Dec 2005

Svetkey LP, Stevens VJ, Brantley PJ, Appel LJ, Hollis JF, Loria CM, Vollmer WM, Gullion CM, Funk K, Smith P, Samuel-Hodge C, Myers M, Lien LF, Laferriere D, Kennedy B, Jerome GJ, Heinith F, Harsha DW, Evans P, Erlinger TP, Dalcin AT, Coughlin J, Charleston J, Champagne CM, Bauck A, Ard JD, Aicher K. “Comparison of Strategies for Sustaining Weight Loss: The Weight Loss Maintenance Randomized Controlled Trial.” JAMA. Vol. 299, No. 10:p. 1139-1148, Mar 2008

Vollmer WM, Stevens VJ, Svetkey LP, Lien LF, Champagne CM. Comprehensive lifestyle modification and blood pressure control. Cardiology Review 2008;25:38-42.

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