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School of Medicine » Sarah W. Stedman Nutrition & Metabolism Center
Faculty & Staff

David Millington, PhDDavid Millington, PhD

Professor
Department of Pediatrics
Co-director, Biochemical and Genetics Laboratory
and Mass Spectrometry Facility
 
David Millington, PhD is a professor in the Department of Pediatrics, Medical Genetics Division and co-director of the Biochemical Genetics Laboratory and Mass Spectrometry Facility at Duke University Medical Center. His expertise in metabolic profiling and broad experience with the development and application of novel clinical diagnostic tests and biomarker assays using mass spectrometry techniques, particularly tandem mass spectrometry, has made him invaluable to the growth of the Stedman Center. He has collaborated with Dr. Christopher Newgard to establish the research-dedicated mass spectrometry laboratory within the Stedman Center, which is part of its current Metabolomics/Biomarker core laboratory. His research is funded mostly from industrial sources, including Genzyme Corporation and GlaxoSmithKline. Dr Millington has published widely in the field of biochemical genetics and his current interests besides his work at the center include the development of biomarker assays for lysosomal storage disorders.

 
Publications:
Haqq AM, Lien LF, Boan J, Arlotto M, Slentz CA, Muehlbauer MJ, Rochon J, Gallup D, McMahon RL, Bain JR, Stevens R, Millington D, Butler MD, Newgard CB, Svetkey LP.  The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design. Contemp Clin Trials. 2005 Dec 26(6):616-25.
 
Wu JY, Kao HJ, Li SC, Stevens RD, Hillman SL, Millington DS, Chen TY. ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. J Clin Invest. 2004;113:434-440.

Millington DS. Tandem Mass Spectrometry in Clinical Diagnosis. In: Blau N, Duran M, Blaskovics ME, Gibson M. eds. Physicians Guide to the Laboratory Diagnosis of Metabolic Diseases. 2nd ed. Berlin, GER: Springer; 2003:57-75.

Young SP, Stevens RD, An Y, Chen YT, Millington DS. Analysis of a glucose tetrasaccharide elevated in Pompe disease by stable isotope dilution-electrospray ionization tandem mass spectrometry. Anal Biochem. 2003;316:175-180.

Millington DS, Koeberl DD. Metabolic Screening in the Newborn. Growth, Genetics & Hormones. 2003;3:33-38.
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